The Massachusetts Institute of Technology ranks No. 5 this year, holding steady from last year and improving upon its No. 7 finish in 2011. Incorporated by the Commonwealth of Massachusetts in 1861, the university's motto is Mens et manus ("Mind and Hand"). It claims 78 Nobel Laureates, 53 National Medal of Science winners, and 27 National Medal of Technology and Innovation winners among its alumni and faculty. More than 200 life science and technology-related companies have offices in MIT's hometown, Cambridge, Mass.

Taylor Weidman/The Christian Science Monitor/File
Students walk through the main administration building on the Massachusetts Institute of Technology campus, in Cambridge, Mass., May 4 2010.