NBC's program ran from 2001 to 2010, switching to the ABC network near the end of its run. The show followed the interns at a teaching hospital, including best friends J.D. (Zach Braff) and Turk (Donald Faison) as well as their love interests Elliot (Sarah Chalke) and Carla (Judy Reyes).
The show's creator, Bill Lawrence, was partially inspired to write the show's storyline after hearing about the experiences of a college acquaintance who was working as an intern at a hospital. The location where the show was filmed, the North Hollywood Medical Center, was actually used as a hospital in the past.
Viewers have pointed out that an X-ray is hung the wrong way in the opening credits in early seasons. Lawrence said the mistake was intentional, while Braff said they hadn't realized the error.