The 1989 movie directed by Rob Reiner stars Meg Ryan as Sally Albright and Billy Crystal as Harry Burns, who first meet while driving cross-country from Chicago to New York and have an argument over whether men and women can truly be friends without romance getting in the way. When they become friends years later, the question gets put to the test.
According to Reiner, Nora Ephron, who wrote the screenplay, based the character of Harry on Reiner himself and Reiner's friend Andy Scheinman.
The film went through several title changes, and Reiner finally told the crew whoever thought of the final name would receive a case of champagne.
